Nikon D300 vs Fujifilm GFX 50S

The Nikon D300 and the Fujifilm GFX 50S are two digital cameras that were officially introduced, respectively, in August 2007 and September 2016. The D300 is a DSLR, while the GFX 50S is a mirrorless interchangeable lens camera. The cameras are based on an APS-C (D300) and a medium format (GFX 50S) sensor. The Nikon has a resolution of 12.2 megapixels, whereas the Fujifilm provides 51.1 MP.

Below is an overview of the main specs of the two cameras as a starting point for the comparison.

Headline Specifications

Nikon D300		Fujifilm GFX 50S
Digital single lens reflex		Mirrorless system camera
Nikon F mount lenses		Fujifilm G mount lenses
12.2 MP – APS-C sensor		51.1 MP – Medium Format sensor
no Video		1080/30p Video
ISO 200-3,200 (100 - 6,400)		ISO 100-12,800 (50 - 102,400)
Optical viewfinder		Viewfinder optional
3.0" LCD – 922k dots		3.2" LCD – 2360k dots
Fixed screen (not touch-sensitive)		Fully flexible touchscreen
6 shutter flaps per second		3 shutter flaps per second
Weathersealed body		Weathersealed body
1000 shots per battery charge		400 shots per battery charge
147 x 114 x 74 mm, 925 g		148 x 94 x 91 mm, 740 g

Check D300 offers at
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Check GFX 50S offers at
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Going beyond this snapshot of core features and characteristics, what are the differences between the Nikon D300 and the Fujifilm GFX 50S? Which one should you buy? Read on to find out how these two cameras compare with respect to their body size, their imaging sensors, their shooting features, their input-output connections, and their reception by expert reviewers.

Body comparison

The physical size and weight of the Nikon D300 and the Fujifilm GFX 50S are illustrated in the side-by-side display below. The two cameras are presented according to their relative size. Three consecutive perspectives from the front, the top, and the back are available. All width, height and depth dimensions are rounded to the nearest millimeter.

If the front view area (width x height) of the cameras is taken as an aggregate measure of their size, the Fujifilm GFX 50S is notably smaller (17 percent) than the Nikon D300. Moreover, the GFX 50S is markedly lighter (20 percent) than the D300. In this context, it is worth noting that both cameras are splash and dust-proof and can, hence, be used in inclement weather conditions or harsh environments.

The above size and weight comparisons are to some extent incomplete since they do not consider the interchangeable lenses that both of these cameras require. Hence, you might want to study and compare the specifications of available lenses in order to get the full picture of the size and weight of the two camera systems.

Concerning battery life, the D300 gets 1000 shots out of its Nikon EN-EL3e battery, while the GFX 50S can take 400 images on a single charge of its Fujifilm NP-T125 power pack.

The following table provides a synthesis of the main physical specifications of the two cameras and other similar ones. In case you want to display and compare another camera duo, you can use the CAM-parator app to select your camera combination among a large number of options.

Body Specifications

		Camera Model	Camera Width	Camera Height	Camera Depth	Camera Weight	Battery Life	Weather Sealing	Camera Launch	Launch Price	Street Price
1.		Nikon D300	147 mm	114 mm	74 mm	925 g	1000	Y	Aug 2007	US$ 1 799	ebay.com
2.		Fujifilm GFX 50S	148 mm	94 mm	91 mm	740 g	400	Y	Sep 2016	US$ 6 499	ebay.com
3.		Fujifilm GFX 50R	161 mm	97 mm	66 mm	775 g	400	Y	Sep 2018	US$ 4 499	ebay.com
4.		Fujifilm GFX 50S II	150 mm	104 mm	87 mm	900 g	440	Y	Sep 2021	US$ 3 999	amazon.com
5.		Hasselblad X1D II	148 mm	97 mm	70 mm	766 g	..	Y	Jun 2019	US$ 5 749	ebay.com
6.		Leica M10	139 mm	80 mm	39 mm	660 g	210	Y	Jan 2017	US$ 6 599	ebay.com
7.		Leica SL	147 mm	104 mm	39 mm	847 g	400	Y	Oct 2015	US$ 7 449	ebay.com
8.		Nikon D2X	158 mm	150 mm	86 mm	1252 g	3800	Y	Sep 2004	US$ 4 999	ebay.com
9.		Nikon D2Xs	158 mm	150 mm	86 mm	1252 g	3800	Y	Jun 2006	US$ 4 699	ebay.com
10.		Nikon D40X	124 mm	94 mm	64 mm	522 g	520	n	Mar 2007	US$ 729	ebay.com
11.		Nikon D60	126 mm	94 mm	64 mm	522 g	500	n	Jan 2008	US$ 629	ebay.com
12.		Nikon D80	132 mm	103 mm	77 mm	668 g	600	n	Aug 2006	US$ 999	ebay.com
13.		Nikon D90	132 mm	103 mm	77 mm	703 g	850	n	Aug 2008	US$ 1 299	ebay.com
14.		Nikon D200	147 mm	113 mm	74 mm	920 g	400	Y	Nov 2005	US$ 1 699	ebay.com
15.		Nikon D300S	147 mm	115 mm	81 mm	938 g	950	Y	Jul 2009	US$ 1 799	ebay.com
16.		Nikon D700	147 mm	123 mm	77 mm	1074 g	1000	Y	Jul 2008	US$ 2 999	ebay.com
17.		Nikon D7000	132 mm	105 mm	77 mm	780 g	1050	Y	Sep 2010	US$ 1 499	ebay.com
Note: Measurements and pricing do not include easily detachable parts, such as add-on or interchangeable lenses or optional viewfinders.
Convert to Imperial

The price is, of course, an important factor in any camera decision. The listed launch prices provide an indication of the market segment that the manufacturer of the cameras have been targeting. The D300 was launched at a markedly lower price (by 72 percent) than the GFX 50S, which puts it into a different market segment. Normally, street prices remain initially close to the MSRP, but after a couple of months, the first discounts appear. Later in the product cycle and, in particular, when the replacement model is about to appear, further discounting and stock clearance sales often push the camera price considerably down. Then, after the new model is out, very good deals can frequently be found on the pre-owned market.

Sensor comparison

The size of the sensor inside a digital camera is one of the key determinants of image quality. A large sensor will tend to have larger individual pixels that provide better low-light sensitivity, wider dynamic range, and richer color-depth than smaller pixel-units in a sensor of the same technological generation. Moreover, a large sensor camera will give the photographer more control over depth-of-field in the image and, thus, the ability to better isolate a subject from the background. On the downside, larger sensors are more costly to manufacture and tend to lead to bigger and heavier cameras and lenses.

Of the two cameras under consideration, the Nikon D300 features an APS-C sensor and the Fujifilm GFX 50S a medium format sensor. The sensor area in the GFX 50S is 289 percent bigger. As a result of these sensor size differences, the cameras have a format factor of, respectively, 1.5 and 0.79. The sensor in the D300 has a native 3:2 aspect ratio, while the one in the GFX 50S offers a 4:3 aspect.

With 51.1MP, the GFX 50S offers a higher resolution than the D300 (12.2MP), but the GFX 50S has smaller individual pixels (pixel pitch of 5.33μm versus 5.53μm for the D300). Yet, the GFX 50S is a much more recent model (by 9 years) than the D300, and its sensor will have benefitted from technological advances during this time that enhance the light gathering capacity of its pixel-units. Coming back to sensor resolution, it should be mentioned that the GFX 50S has no anti-alias filter installed, so that it can capture all the detail its sensor resolves.

The resolution advantage of the Fujifilm GFX 50S implies greater flexibility for cropping images or the possibility to print larger pictures. The maximum print size of the GFX 50S for good quality output (200 dots per inch) amounts to 41.3 x 31 inches or 104.9 x 78.6 cm, for very good quality (250 dpi) 33 x 24.8 inches or 83.9 x 62.9 cm, and for excellent quality (300 dpi) 27.5 x 20.6 inches or 69.9 x 52.4 cm. The corresponding values for the Nikon D300 are 21.4 x 14.2 inches or 54.5 x 36.2 cm for good quality, 17.2 x 11.4 inches or 43.6 x 28.9 cm for very good quality, and 14.3 x 9.5 inches or 36.3 x 24.1 cm for excellent quality prints.

The Nikon D300 has a native sensitivity range from ISO 200 to ISO 3200, which can be extended to ISO 100-6400. The corresponding ISO settings for the Fujifilm GFX 50S are ISO 100 to ISO 12800, with the possibility to increase the ISO range to 50-102400.

Technology-wise, both cameras are equipped with CMOS (Complementary Metal–Oxide–Semiconductor) sensors. Both cameras use a Bayer filter for capturing RGB colors on a square grid of photosensors. This arrangement is found in most digital cameras.

For many cameras, data on sensor performance has been reported by DXO Mark. This service assesses and scores the color depth ("DXO Portrait"), dynamic range ("DXO Landscape"), and low-light sensitivity ("DXO Sports") of camera sensors, and also publishes an overall camera score. The following table provides an overview of the physical sensor characteristics, as well as the sensor quality measurements for a selection of comparators.

Sensor Characteristics

		Camera Model	Sensor Class	Resolution (MP)	Horiz. Pixels	Vert. Pixels	Video Format	DXO Portrait	DXO Landscape	DXO Sports	DXO Overall
1.		Nikon D300	APS-C	12.2	4288	2848	none	22.1	12.0	679	67
2.		Fujifilm GFX 50S	Medium Format	51.1	8256	6192	1080/30p	25.4	14.1	2977	96
3.		Fujifilm GFX 50R	Medium Format	51.1	8256	6192	1080/30p	25.7	14.4	3169	98
4.		Fujifilm GFX 50S II	Medium Format	51.1	8256	6192	1080/30p	25.9	14.8	3456	100
5.		Hasselblad X1D II	Medium Format	51.3	8272	6200	1080/25p	25.7	14.5	3234	99
6.		Leica M10	Full Frame	23.8	5952	3992	none	24.4	13.2	2133	86
7.		Leica SL	Full Frame	24.0	6000	4000	4K/30p	25.0	13.4	1821	88
8.		Nikon D2X	APS-C	12.2	4288	2848	none	22.1	10.9	476	59
9.		Nikon D2Xs	APS-C	12.2	4288	2848	none	22.2	10.9	489	59
10.		Nikon D40X	APS-C	10.0	3872	2592	none	22.4	11.4	516	63
11.		Nikon D60	APS-C	10.0	3872	2592	none	22.5	11.4	562	65
12.		Nikon D80	APS-C	10.0	3872	2592	none	22.1	11.2	524	61
13.		Nikon D90	APS-C	12.2	4288	2848	720/24p	22.7	12.5	977	73
14.		Nikon D200	APS-C	10.0	3872	2592	none	22.3	11.5	583	64
15.		Nikon D300S	APS-C	12.2	4288	2848	720/24p	22.5	12.2	787	70
16.		Nikon D700	Full Frame	12.1	4256	2832	none	23.5	12.2	2303	80
17.		Nikon D7000	APS-C	16.1	4928	3264	1080/24p	23.5	13.9	1167	80
Note: DXO values in italics represent estimates based on sensor size and age.

Many modern cameras are not only capable of taking still images, but also of capturing video footage. The GFX 50S indeed provides for movie recording, while the D300 does not. The highest resolution format that the GFX 50S can use is 1080/30p.

Feature comparison

Apart from body and sensor, cameras can and do differ across a variety of features. For example, the D300 has an optical viewfinder, which can be very useful when shooting in bright sunlight. In contrast, the GFX 50S relies on live view and the rear LCD for framing. That said, the GFX 50S can be equipped with an optional viewfinder – the EVF-TL1. The adjacent table lists some of the other core features of the Nikon D300 and Fujifilm GFX 50S along with similar information for a selection of comparators.

Core Features

		Camera Model	Viewfinder (Type or 000 dots)	Control Panel (yes/no)	LCD Specifications (inch/000 dots)	LCD Attach- ment	Touch Screen (yes/no)	Max Shutter Speed *	Max Shutter Flaps *	Built-in Flash (yes/no)	Built-in Image Stab
1.		Nikon D300	optical	Y	3.0 / 922	fixed	n	1/8000s	6.0/s	Y	n
2.		Fujifilm GFX 50S	optional	Y	3.2 / 2360	full-flex	Y	1/4000s	3.0/s	n	n
3.		Fujifilm GFX 50R	3690	n	3.2 / 2360	tilting	Y	1/4000s	3.0/s	n	n
4.		Fujifilm GFX 50S II	3690	Y	3.2 / 2360	full-flex	Y	1/4000s	3.0/s	n	Y
5.		Hasselblad X1D II	3690	n	3.6 / 2360	fixed	Y	1/2000s	2.7/s	n	n
6.		Leica M10	optical	n	3.0 / 1037	fixed	n	1/4000s	5.0/s	n	n
7.		Leica SL	4400	Y	3.0 / 1040	fixed	Y	1/8000s	11.0/s	n	n
8.		Nikon D2X	optical	Y	2.5 / 235	fixed	n	1/8000s	5.0/s	n	n
9.		Nikon D2Xs	optical	Y	2.5 / 230	fixed	n	1/8000s	5.0/s	n	n
10.		Nikon D40X	optical	n	2.5 / 230	fixed	n	1/4000s	3.0/s	Y	n
11.		Nikon D60	optical	n	2.5 / 230	fixed	n	1/4000s	3.0/s	Y	n
12.		Nikon D80	optical	n	2.5 / 230	fixed	n	1/4000s	3.0/s	Y	n
13.		Nikon D90	optical	Y	3.0 / 920	fixed	n	1/4000s	4.5/s	Y	n
14.		Nikon D200	optical	Y	2.5 / 230	fixed	n	1/8000s	5.0/s	Y	n
15.		Nikon D300S	optical	Y	3.0 / 920	fixed	n	1/8000s	7.0/s	Y	n
16.		Nikon D700	optical	Y	3.0 / 922	fixed	n	1/8000s	8.0/s	Y	n
17.		Nikon D7000	optical	Y	3.0 / 921	fixed	n	1/8000s	6.0/s	Y	n
Note: *) Information refers to the mechanical shutter, unless the camera only has an electronic one.

One difference between the cameras concerns the presence of an on-board flash. The D300 has one, while the GFX 50S does not. While the built-in flash of the D300 is not very powerful, it can at times be useful as a fill-in light.

The reported shutter speed information refers to the use of the mechanical shutter. Yet, some cameras only have an electronic shutter, while others have an electronic shutter in addition to a mechanical one. In fact, the GFX 50S is one of those camera that have an additional electronic shutter, which makes completely silent shooting possible. However, this mode is less suitable for photographing moving objects (risk of rolling shutter) or shooting under artificial light sources (risk of flickering).

The Nikon D300 and the Fujifilm GFX 50S both have an intervalometer built-in. This enables the photographer to capture time lapse sequences, such as flower blooming, a sunset or moon rise, without purchasing an external camera trigger and related software.

The D300 writes its imaging data to Compact Flash cards, while the GFX 50S uses SDXC cards. The GFX 50S features dual card slots, which can be very useful in case a memory card fails. In contrast, the D300 only has one slot.

Connectivity comparison

For some imaging applications, the extent to which a camera can communicate with its environment can be an important aspect in the camera decision process. The table below provides an overview of the connectivity of the Nikon D300 and Fujifilm GFX 50S and, in particular, the interfaces the cameras (and selected comparators) provide for accessory control and data transfer.

Input-Output Connections

		Camera Model	Hotshoe Port	Internal Mic / Speaker	Microphone Port	Headphone Port	HDMI Port	USB Port	WiFi Support	NFC Support	Bluetooth Support
1.		Nikon D300	Y	- / -	-	-	mini	2.0	-	-	-
2.		Fujifilm GFX 50S	Y	stereo / mono	Y	Y	micro	3.0	Y	-	-
3.		Fujifilm GFX 50R	Y	stereo / mono	Y	Y	micro	3.0	Y	-	Y
4.		Fujifilm GFX 50S II	Y	stereo / mono	Y	Y	micro	3.2	Y	-	-
5.		Hasselblad X1D II	Y	stereo / mono	Y	Y	-	3.0	Y	-	-
6.		Leica M10	Y	- / -	-	-	-	-	Y	-	-
7.		Leica SL	Y	stereo / mono	Y	Y	full	3.0	Y	-	-
8.		Nikon D2X	Y	- / -	-	-	-	2.0	-	-	-
9.		Nikon D2Xs	Y	- / -	-	-	-	2.0	-	-	-
10.		Nikon D40X	Y	- / -	-	-	-	2.0	-	-	-
11.		Nikon D60	Y	- / -	-	-	-	2.0	-	-	-
12.		Nikon D80	Y	- / -	-	-	-	2.0	-	-	-
13.		Nikon D90	Y	mono / mono	-	-	mini	2.0	-	-	-
14.		Nikon D200	Y	- / -	-	-	-	2.0	-	-	-
15.		Nikon D300S	Y	stereo / mono	Y	-	mini	2.0	-	-	-
16.		Nikon D700	Y	- / -	-	-	mini	2.0	-	-	-
17.		Nikon D7000	Y	mono / mono	Y	-	mini	2.0	-	-	-

It is notable that the GFX 50S offers wifi support, which can be a very convenient means to transfer image data to an off-camera location. In contrast, the D300 does not provide wifi capability.

Both cameras feature a PC Sync terminal to control professional strobe lights, which will be appreciated by studio photographers.

Both the D300 and the GFX 50S have been discontinued, but can regularly be found used on ebay. The D300 was replaced by the Nikon D300S, while the GFX 50S was followed by the Fujifilm GFX 50S II. Further information on the features and operation of the D300 and GFX 50S can be found, respectively, in the Nikon D300 Manual (free pdf) or the online Fujifilm GFX 50S Manual.

Review summary

So what is the bottom line? Which of the two cameras – the Nikon D300 or the Fujifilm GFX 50S – has the upper hand? Is one clearly better than the other? A synthesis of the relative strong points of each of the models is listed below.

Arguments in favor of the Nikon D300:

• Better moiré control: Has an anti-alias filter to avoid artificial patterns to appear in images.
• Easier framing: Has an optical viewfinder for image composition and settings control.
• Faster shutter: Has higher mechanical shutter speed (1/8000s vs 1/4000s) to freeze action.
• Faster burst: Shoots at higher frequency (6 vs 3 flaps/sec) to capture the decisive moment.
• Longer lasting: Can take more shots (1000 versus 400) on a single battery charge.
• Easier fill-in: Is equipped with a small onboard flash to brighten deep shadow areas.
• More affordable: Was introduced into a lower priced category (72 percent cheaper at launch).
• More heavily discounted: Has been available for much longer (launched in August 2007).

Advantages of the Fujifilm GFX 50S:

• More detail: Has more megapixels (51.1 vs 12.2MP), which boosts linear resolution by 100%.
• Maximized detail: Lacks an anti-alias filter to exploit the sensor's full resolution potential.
• Better image quality: Is equipped with a larger and more technologically advanced sensor.
• Richer colors: The sensor size advantage translates into images with better, more accurate colors.
• More dynamic range: Larger sensor captures a wider spectrum of light and dark details.
• Better low-light sensitivity: Larger sensor produces good images even in poorly lit environments.
• Broader imaging potential: Can capture not only stills but also 1080/30p video.
• Larger screen: Has a bigger rear LCD (3.2" vs 3.0") for image review and settings control.
• More detailed LCD: Has a higher resolution rear screen (2360k vs 922k dots).
• More flexible LCD: Has a full-flex screen for odd-angle shots in portrait or landscape orientation.
• Fewer buttons to press: Has a touchscreen to facilitate handling and shooting adjustments.
• Less disturbing: Has an electronic shutter option for completely silent shooting.
• More compact: Is smaller (148x94mm vs 147x114mm) and will fit more readily into a bag.
• Less heavy: Has a lower weight (by 185g or 20 percent) and is thus easier to take along.
• More legacy lens friendly: Can use many non-native lenses via adapters.
• Faster data transfer: Supports a more advanced USB protocol (3.0 vs 2.0).
• Easier file upload: Has wifi built in for automatic backup or image transfer to the web.
• Greater peace of mind: Features a second card slot as a backup in case of memory card failure.
• More modern: Reflects 9 years of technical progress since the D300 launch.

If the count of relative strengths (bullet points above) is taken as a measure, the GFX 50S is the clear winner of the contest (19 : 8 points). However, the pertinence of the various camera strengths will differ across photographers, so that you might want to weigh individual camera traits according to their importance for your own imaging needs before making a camera decision. A professional wedding photographer will view the differences between cameras in a way that diverges from the perspective of a travel photog, and a person interested in cityscapes has distinct needs from a macro shooter. Hence, the decision which camera is best and worth buying is often a very personal one.

How about other alternatives? Do the specifications of the Nikon D300 and the Fujifilm GFX 50S place the cameras among the top in their class? Find out in the latest Best DSLR Camera and Best Mirrorless Interchangeable Lens Camera listings whether the two cameras rank among the cream of the crop.

In any case, while the comparison of the spec-sheets of cameras can offer a general idea of their imaging potential, it says little about, for example, the shooting experience and imaging performance of the D300 and the GFX 50S in practical situations. At times, user reviews, such as those published at amazon, address these issues in a useful manner, but such feedback is on many occasions incomplete, inconsistent, and unreliable.

Expert reviews

This is why expert reviews are important. The table below provides a synthesis of the camera assessments of some of the best known photo-gear review sites (amateurphotographer [AP], cameralabs [CL], digitalcameraworld [DCW], dpreview [DPR], ephotozine [EPZ], photographyblog [PB]). As can be seen, the professional reviewers agree in many cases on the quality of different cameras, but sometimes their assessments diverge, reinforcing the earlier point that a camera decision is often a very personal choice.

Expert Camera Reviews

		Camera   Model	AP   score	CL   score	DCW   score	DPR   score	EPZ   score	PB   score	Camera Launch	Launch Price	Street Price
1.		Nikon D300	..	+ +	..	+ +	5/5	4.5/5	Aug 2007	US$ 1 799	ebay.com
2.		Fujifilm GFX 50S	..	..	4.5/5	85/100	5/5	4.5/5	Sep 2016	US$ 6 499	ebay.com
3.		Fujifilm GFX 50R	5/5	..	5/5	84/100	4.5/5	4.5/5	Sep 2018	US$ 4 499	ebay.com
4.		Fujifilm GFX 50S II	5/5	..	5/5	87/100	..	5/5	Sep 2021	US$ 3 999	amazon.com
5.		Hasselblad X1D II	..	..	4/5	..	4/5	4/5	Jun 2019	US$ 5 749	ebay.com
6.		Leica M10	4.5/5	..	..	..	4/5	4.5/5	Jan 2017	US$ 6 599	ebay.com
7.		Leica SL	4/5	..	4/5	84/100	4.5/5	4/5	Oct 2015	US$ 7 449	ebay.com
8.		Nikon D2X	..	..	..	+ +	..	..	Sep 2004	US$ 4 999	ebay.com
9.		Nikon D2Xs	..	..	..	..	..	..	Jun 2006	US$ 4 699	ebay.com
10.		Nikon D40X	..	79/100	..	+ +	4/5	4/5	Mar 2007	US$ 729	ebay.com
11.		Nikon D60	..	80/100	..	+ +	4/5	4.5/5	Jan 2008	US$ 629	ebay.com
12.		Nikon D80	..	+	..	+ +	o	4.5/5	Aug 2006	US$ 999	ebay.com
13.		Nikon D90	..	+ +	..	+ +	4/5	4.5/5	Aug 2008	US$ 1 299	ebay.com
14.		Nikon D200	..	+ +	..	+ +	o	..	Nov 2005	US$ 1 699	ebay.com
15.		Nikon D300S	5/5	+ +	..	82/100	4/5	4.5/5	Jul 2009	US$ 1 799	ebay.com
16.		Nikon D700	..	89/100	..	+ +	4.5/5	4.5/5	Jul 2008	US$ 2 999	ebay.com
17.		Nikon D7000	4/5	..	..	80/100	4.5/5	4.5/5	Sep 2010	US$ 1 499	ebay.com
Note: (+ +) highly recommended; (+) recommended; (o) reviewed; (..) not available.

The above review scores should be interpreted with care, though. The ratings are only valid when referring to cameras in the same category and of the same age. A score, therefore, has to be seen in close connection to the price and market introduction time of the camera, and comparisons of ratings among very different cameras or across long time periods have little meaning. Also, please note that some of the review sites have changed their methodology and reporting over time.

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Other camera comparisons

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