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Nikon D4S vs Pentax 645D

The Nikon D4S and the Pentax 645D are two professional cameras that were revealed to the public, respectively, in February 2014 and March 2010. Both are DSLR (Digital Single Lens Reflex) cameras that are based on a full frame (D4S) and a medium format (645D) sensor. The Nikon has a resolution of 16.2 megapixels, whereas the Pentax provides 39.5 MP.

Below is an overview of the main specs of the two cameras as a starting point for the comparison.

Headline Specifications
Nikon D4S
versus
Pentax 645D
Nikon D4S   Pentax 645D
Digital single lens reflex Digital single lens reflex
Nikon F mount lenses Pentax 645 mount lenses
16.2 MP – Full Frame sensor 39.5 MP – Medium Format sensor
1080/60p Video no Video
ISO 100-25,600 (50 - 409,600) ISO 100-1,600
Optical viewfinder Optical viewfinder
3.2" LCD – 921k dots 3.0" LCD – 921k dots
Fixed screen (not touch-sensitive) Fixed screen (not touch-sensitive)
11 shutter flaps per second 1.1 shutter flaps per second
Weathersealed bodyWeathersealed body
3020 shots per battery charge800 shots per battery charge
160 x 157 x 91 mm, 1350 g 156 x 117 x 119 mm, 1480 g
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Going beyond this snapshot of core features and characteristics, what are the differences between the Nikon D4S and the Pentax 645D? Which one should you buy? Read on to find out how these two cameras compare with respect to their body size, their imaging sensors, their shooting features, their input-output connections, and their reception by expert reviewers.

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Body comparison

An illustration of the physical size and weight of the Nikon D4S and the Pentax 645D is provided in the side-by-side display below. The two cameras are presented according to their relative size. Three successive views from the front, the top, and the rear are shown. All size dimensions are rounded to the nearest millimeter.

Size Nikon D4S vs Pentax 645D
Compare D4S versus 645D top
Comparison D4S or 645D rear

If the front view area (width x height) of the cameras is taken as an aggregate measure of their size, the Pentax 645D is notably smaller (27 percent) than the Nikon D4S. However, the 645D is markedly heavier (10 percent) than the D4S. In this context, it is worth noting that both cameras are splash and dust-proof and can, hence, be used in inclement weather conditions or harsh environments.

The above size and weight comparisons are to some extent incomplete since they do not consider the interchangeable lenses that both of these cameras require. Hence, you might want to study and compare the specifications of available lenses in order to get the full picture of the size and weight of the two camera systems.

Concerning battery life, the D4S gets 3020 shots out of its Nikon EN-EL18a battery, while the 645D can take 800 images on a single charge of its Pentax D-LI90 power pack. As can be seen in the images above, the D4S has a battery grip built in. This facilitates image-taking in portrait orientation and gives it additional battery power.

The table below summarizes the key physical specs of the two cameras alongside a broader set of comparators. If you want to switch the focus of the display and review another camera pair, you can move across to the CAM-parator tool and choose from the broad selection of possible camera comparisons there.

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Body Specifications
# image Camera
Model
Camera
Width
Camera
Height
Camera
Depth
Camera
Weight
Battery
Life
Weather
Sealing
Camera
Launch
Launch
Price (USD)
Street
Price
1.
 
Nikon D4S 160 mm 157 mm 91 mm 1350 g 3020 Y Feb 2014 6,499ebay.com
2.
 
Pentax 645D 156 mm 117 mm 119 mm 1480 g 800 Y Mar 2010 9,995ebay.com
3.
 
Canon 1D X 158 mm 168 mm 83 mm 1551 g 1120 Y Oct 2011 6,799ebay.com
4.
 
Canon 1D Mark IV 156 mm 157 mm 80 mm 1230 g 1500 Y Oct 2009 4,999ebay.com
5.
 
Leica S Typ 006 160 mm 120 mm 80 mm 1260 g .. Y Sep 2012 21,950ebay.com
6.
 
Nikon D6 160 mm 163 mm 92 mm 1270 g 3580 Y Feb 2020 6,499 amazon.com
7.
 
Nikon D5 160 mm 159 mm 92 mm 1415 g 3780 Y Jan 2016 6,499ebay.com
8.
 
Nikon D750 141 mm 113 mm 78 mm 750 g 1230 Y Sep 2014 2,299ebay.com
9.
 
Nikon D810 146 mm 123 mm 82 mm 980 g 1200 Y Jun 2014 3,299ebay.com
10.
 
Nikon Df 144 mm 110 mm 67 mm 760 g 1400 Y Nov 2013 2,749ebay.com
11.
 
Nikon D4 160 mm 157 mm 91 mm 1340 g 2600 Y Jan 2012 5,999ebay.com
12.
 
Nikon D3S 160 mm 157 mm 88 mm 1240 g 4200 Y Oct 2009 5,199ebay.com
13.
 
Nikon D3X 160 mm 157 mm 88 mm 1260 g 4400 Y Dec 2008 7,999ebay.com
14.
 
Nikon D3 160 mm 157 mm 88 mm 1300 g 4300 Y Aug 2007 4,999ebay.com
15.
 
Pentax 645Z 156 mm 117 mm 123 mm 1550 g 650 Y Apr 2014 8,499ebay.com
Note: Measurements and pricing do not include easily detachable parts, such as add-on or interchangeable lenses or optional viewfinders.
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Any camera decision will obviously take relative prices into account. The manufacturer’s suggested retail prices give an idea on the placement of the camera in the maker’s lineup and the broader market. The D4S was launched at a markedly lower price (by 35 percent) than the 645D, which puts it into a different market segment. Normally, street prices remain initially close to the MSRP, but after a couple of months, the first discounts appear. Later in the product cycle and, in particular, when the replacement model is about to appear, further discounting and stock clearance sales often push the camera price considerably down.

Sensor comparison

The size of the imaging sensor is a crucial determinant of image quality. A large sensor will tend to have larger individual pixels that provide better low-light sensitivity, wider dynamic range, and richer color-depth than smaller pixel-units in a sensor of the same technological generation. Moreover, a large sensor camera will give the photographer more control over depth-of-field in the image and, thus, the ability to better isolate a subject from the background. On the downside, larger sensors tend to be more expensive and lead to bigger and heavier cameras and lenses.

Of the two cameras under consideration, the Nikon D4S features a full frame sensor and the Pentax 645D a medium format sensor. The sensor area in the 645D is 69 percent bigger. As a result of these sensor size differences, the cameras have a format factor of, respectively, 1.0 and 0.79. The sensor in the D4S has a native 3:2 aspect ratio, while the one in the 645D offers a 4:3 aspect.

Nikon D4S and Pentax 645D sensor measures

With 39.5MP, the 645D offers a higher resolution than the D4S (16.2MP), but the 645D has smaller individual pixels (pixel pitch of 6.06μm versus 7.29μm for the D4S). Yet, the D4S is a much more recent model (by 3 years and 11 months) than the 645D, and its sensor will have benefitted from technological advances during this time that further enhance the light gathering capacity of its pixel-units. Coming back to sensor resolution, it should be mentioned that the 645D has no anti-alias filter installed, so that it can capture all the detail its sensor resolves.

The resolution advantage of the Pentax 645D implies greater flexibility for cropping images or the possibility to print larger pictures. The maximum print size of the 645D for good quality output (200 dots per inch) amounts to 36.3 x 27.2 inches or 92.3 x 69.1 cm, for very good quality (250 dpi) 29.1 x 21.8 inches or 73.8 x 55.3 cm, and for excellent quality (300 dpi) 24.2 x 18.1 inches or 61.5 x 46.1 cm. The corresponding values for the Nikon D4S are 24.6 x 16.4 inches or 62.6 x 41.7 cm for good quality, 19.7 x 13.1 inches or 50.1 x 33.3 cm for very good quality, and 16.4 x 10.9 inches or 41.7 x 27.8 cm for excellent quality prints.

The Nikon D4S has a native sensitivity range from ISO 100 to ISO 25600, which can be extended to ISO 50-409600. The corresponding ISO settings for the Pentax 645D are ISO 100 to ISO 1600 (no boost).

In terms of underlying technology, the D4S is build around a CMOS sensor, while the 645D uses a CCD imager. Both cameras use a Bayer filter for capturing RGB colors on a square grid of photosensors. This arrangement is found in most digital cameras.

D4S versus 645D MP

Consistent information on actual sensor performance is available from DXO Mark for many cameras. This service determines an overall sensor rating, as well as sub-scores for low-light sensitivity ("DXO Sports"), dynamic range ("DXO Landscape"), and color depth ("DXO Portrait"). Of the two cameras under review, the D4S has a notably higher overall DXO score than the 645D (overall score 7 points higher), which gives it an advantage in terms of imaging quality. This advantage is based on 0.2 bits lower color depth, 0.7 EV in additional dynamic range, and 1.3 stops in additional low light sensitivity. The following table provides an overview of the physical sensor characteristics, as well as the sensor quality measurements for a selection of comparators.

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Sensor Characteristics
# image Camera
Model
Sensor
Class
Resolution
(MP)
Horiz.
Pixels
Vert.
Pixels
Video
Format
DXO
Portrait
DXO
Landscape
DXO
Sports
DXO
Overall
1.
 
Nikon D4S Full Frame 16.2 4928 32801080/60p24.413.3307489
2.
 
Pentax 645D Medium Format 39.5 7264 5440none24.612.6126282
3.
 
Canon 1D X Full Frame 17.9 5184 34561080/30p23.811.8278682
4.
 
Canon 1D Mark IV APS-H 16.0 4896 32641080/30p22.812.0132074
5.
 
Leica S Typ 006 Medium Format 37.5 7500 5000none23.912.282476
6.
 
Nikon D6 Full Frame 20.7 5568 37124K/30p25.314.3288695
7.
 
Nikon D5 Full Frame 20.7 5588 37124K/30p25.112.3234388
8.
 
Nikon D750 Full Frame 24.2 6016 40161080/60p24.814.5295693
9.
 
Nikon D810 Full Frame 36.2 7360 49121080/60p25.714.8285397
10.
 
Nikon Df Full Frame 16.2 4928 3280none24.613.1327989
11.
 
Nikon D4 Full Frame 16.2 4928 32801080/30p24.713.1296589
12.
 
Nikon D3S Full Frame 12.1 4256 2832720/24p23.512.0325382
13.
 
Nikon D3X Full Frame 24.4 6048 4032none24.713.7199288
14.
 
Nikon D3 Full Frame 12.1 4256 2832none23.512.2229081
15.
 
Pentax 645Z Medium Format 51.1 8256 61921080/60i26.014.74505101
Note: DXO values in italics represent estimates based on sensor size and age.
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Many modern cameras cannot only take still pictures, but also record videos. The D4S indeed provides movie recording capabilities, while the 645D does not. The highest resolution format that the D4S can use is 1080/60p.

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Feature comparison

Apart from body and sensor, cameras can and do differ across a range of features. The D4S and the 645D are similar in the sense that both have an optical viewfinder. The latter is useful for getting a clear image for framing even in brightly lit environments. The viewfinder in the D4S offers a wider field of view (100%) than the one in the 645D (98%), so that a larger proportion of the captured image is visible in the finder. On the other hand, the viewfinder of the 645D has a higher magnification (0.78x vs 0.70x), so that the size of the image transmitted appears closer to the size seen with the naked human eye. The table below summarizes some of the other core capabilities of the Nikon D4S and Pentax 645D in connection with corresponding information for a sample of similar cameras.

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Core Features
# image Camera
Model
Viewfinder
(Type or
000 dots)
Control
Panel
(yes/no)
LCD
Specifications
(inch/000 dots)
LCD
Attach-
ment
Touch
Screen
(yes/no)
Max
Shutter
Speed *
Max
Shutter
Flaps *
Built-in
Flash
(yes/no)
Built-in
Image
Stab
1.
 
Nikon D4Soptical Y3.2 / 921 fixed n 1/8000s 11.0/s n n
2.
 
Pentax 645Doptical Y3.0 / 921 fixed n 1/4000s 1.1/s n n
3.
 
Canon 1D Xoptical Y3.2 / 1040 fixed n 1/8000s 14.0/s n n
4.
 
Canon 1D Mark IVoptical Y3.0 / 920 fixed n 1/8000s 10.0/s n n
5.
 
Leica S Typ 006optical Y3.0 / 922 fixed n 1/4000s 1.5/s n n
6.
 
Nikon D6optical Y3.2 / 2359 fixed Y 1/8000s 14.0/s n n
7.
 
Nikon D5optical Y3.2 / 2359 fixed Y 1/8000s 14.0/s n n
8.
 
Nikon D750optical Y3.2 / 1229 tilting n 1/4000s 6.0/s Y n
9.
 
Nikon D810optical Y3.2 / 1229 fixed n 1/8000s 5.0/s Y n
10.
 
Nikon Dfoptical Y3.2 / 921 fixed n 1/4000s 5.5/s n n
11.
 
Nikon D4optical Y3.2 / 921 fixed n 1/8000s 11.0/s n n
12.
 
Nikon D3Soptical Y3.0 / 921 fixed n 1/8000s 11.0/s n n
13.
 
Nikon D3Xoptical Y3.0 / 922 fixed n 1/8000s 5.0/s n n
14.
 
Nikon D3optical Y3.0 / 922 fixed n 1/8000s 11.0/s n n
15.
 
Pentax 645Zoptical Y3.2 / 1037 tilting n 1/4000s 3.0/s n n
Note: *) Information refers to the mechanical shutter, unless the camera only has an electronic one.
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The Nikon D4S and the Pentax 645D both have an intervalometer built-in. This enables the photographer to capture time lapse sequences, such as flower blooming, a sunset or moon rise, without purchasing an external camera trigger and related software.

The D4S writes its imaging data to Compact Flash or XQD cards, while the 645D uses SDXC cards. Both cameras feature dual card slots, which can be very useful in case a memory card fails.

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Connectivity comparison

For some imaging applications, the extent to which a camera can communicate with its environment can be an important aspect in the camera decision process. The table below provides an overview of the connectivity of the Nikon D4S and Pentax 645D and, in particular, the interfaces the cameras (and selected comparators) provide for accessory control and data transfer.

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Input-Output Connections
# image Camera
Model
Hotshoe
Port
Internal
Mic / Speaker
Microphone
Port
Headphone
Port
HDMI
Port
USB
Port
WiFi
Support
NFC
Support
Bluetooth
Support
1.
 
Nikon D4SYmono / monoYYmini2.0---
2.
 
Pentax 645DYstereo / ----2.0---
3.
 
Canon 1D XYmono / -Y-mini2.0---
4.
 
Canon 1D Mark IVYstereo / -Y-mini2.0---
5.
 
Leica S Typ 006Y- / ---mini2.0---
6.
 
Nikon D6Ystereo / monoYYmini3.1Y-Y
7.
 
Nikon D5Ystereo / monoYYmini3.0---
8.
 
Nikon D750Ystereo / monoYYmini2.0Y--
9.
 
Nikon D810Ystereo / monoYYmini3.0Y--
10.
 
Nikon DfY- / ---mini2.0---
11.
 
Nikon D4Ymono / monoYYmicro2.0---
12.
 
Nikon D3SYstereo / ---mini2.0---
13.
 
Nikon D3XY- / ---mini2.0---
14.
 
Nikon D3Y- / ---mini2.0---
15.
 
Pentax 645ZYstereo / monoY-mini3.0---
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Both cameras feature a PC Sync terminal to control professional strobe lights, which will be appreciated by studio photographers.

Both the D4S and the 645D have been discontinued, but can regularly be found used on ebay. The 645D was replaced by the Pentax 645Z, while the D4S was followed by the Nikon D5. Further information on the features and operation of the D4S and 645D can be found, respectively, in the Nikon D4S Manual (free pdf) or the online Pentax 645D Manual.

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Review summary

So what is the bottom line? Is there a clear favorite between the Nikon D4S and the Pentax 645D? Which camera is better? The listing below highlights the relative strengths of the two models.

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Advantages of the Nikon D4S:

  • Better moiré control: Has an anti-alias filter to avoid artificial patterns to appear in images.
  • Better image quality: Scores markedly higher (7 points) in the DXO overall assessment.
  • More dynamic range: Captures a larger spectrum of light and dark details (0.7 EV of extra DR).
  • Better low-light sensitivity: Requires less light for good images (1.3 stops ISO advantage).
  • Broader imaging potential: Can record not only still images but also 1080/60p movies.
  • More complete view: Has a viewfinder with a larger field of view (100% vs 98%).
  • Larger screen: Has a bigger rear LCD (3.2" vs 3.0") for image review and settings control.
  • Faster shutter: Has higher mechanical shutter speed (1/8000s vs 1/4000s) to freeze action.
  • Faster burst: Shoots at higher frequency (11 vs 1.1 flaps/sec) to capture the decisive moment.
  • More portrait friendly: Features an integrated vertical grip for easier portrait shooting.
  • Longer lasting: Can take more shots (3020 versus 800) on a single battery charge.
  • More affordable: Was introduced into a lower priced category (35 percent cheaper at launch).
  • More modern: Reflects 3 years and 11 months of technical progress since the 645D launch.

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Reasons to prefer the Pentax 645D:

  • More detail: Has more megapixels (39.5 vs 16.2MP), which boosts linear resolution by 53%.
  • Maximized detail: Lacks an anti-alias filter to exploit the sensor's full resolution potential.
  • Larger viewfinder image: Features a viewfinder with a higher magnification (0.78x vs 0.70x).
  • More compact: Is smaller (156x117mm vs 160x157mm) and will fit more readily into a bag.
  • More heavily discounted: Has been around for much longer (launched in March 2010).

If the count of individual advantages (bullet points above) is taken as a guide, the D4S is the clear winner of the match-up (13 : 5 points). However, the pertinence of the various camera strengths will differ across photographers, so that you might want to weigh individual camera traits according to their importance for your own imaging needs before making a camera decision. A professional wildlife photographer will view the differences between cameras in a way that diverges from the perspective of a family photog, and a person interested in architecture has distinct needs from a sports shooter. Hence, the decision which camera is best and worth buying is often a very personal one.

D4S 13:05 645D

How about other alternatives? Do the specifications of the Nikon D4S and the Pentax 645D place the cameras among the top in their class? Find out in the latest Best DSLR Camera listing whether the two cameras rank among the cream of the crop.

In any case, while the comparison of the spec-sheets of cameras can offer a general idea of their imaging potential, it remains incomplete and does no justice, for example, to the way the D4S or the 645D perform in practice. User reviews that are available, for instance, at amazon can sometimes shed light on these issues, but such feedback is all too often partial, inconsistent, and inaccurate.

Expert reviews

This is where reviews by experts come in. The adjacent summary-table relays the overall verdicts of several of the most popular camera review sites (amateurphotographer [AP], cameralabs [CL], digitalcameraworld [DCW], dpreview [DPR], ephotozine [EPZ], photographyblog [PB]). As can be seen, the professional reviewers agree in many cases on the quality of different cameras, but sometimes their assessments diverge, reinforcing the earlier point that a camera decision is often a very personal choice.

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Expert Camera Reviews
# image  Camera 
 Model 
 AP 
 score 
 CL 
 score 
 DCW 
 score 
 DPR 
 score 
 EPZ 
 score 
 PB 
 score 
Camera
Launch
Launch
Price (USD)
Street
Price
1.
 
Nikon D4S5/5......4.5/54.5/5 Feb 2014 6,499ebay.com
2.
 
Pentax 645D5/5.......... Mar 2010 9,995ebay.com
3.
 
Canon 1D X5/5......4.5/54.5/5 Oct 2011 6,799ebay.com
4.
 
Canon 1D Mark IV5/5....89/100.... Oct 2009 4,999ebay.com
5.
 
Leica S Typ 006............ Sep 2012 21,950ebay.com
6.
 
Nikon D6....4/5..4.5/54.5/5 Feb 2020 6,499 amazon.com
7.
 
Nikon D5....4/589/1004.5/55/5 Jan 2016 6,499ebay.com
8.
 
Nikon D7505/5+ +4/590/1004.5/54.5/5 Sep 2014 2,299ebay.com
9.
 
Nikon D8105/5..5/586/1005/54.5/5 Jun 2014 3,299ebay.com
10.
 
Nikon Df4/5....81/1004/54/5 Nov 2013 2,749ebay.com
11.
 
Nikon D4........4.5/54.5/5 Jan 2012 5,999ebay.com
12.
 
Nikon D3S5/5....89/1004.5/55/5 Oct 2009 5,199ebay.com
13.
 
Nikon D3X......86/1004/55/5 Dec 2008 7,999ebay.com
14.
 
Nikon D3......+ +5/54.5/5 Aug 2007 4,999ebay.com
15.
 
Pentax 645Z5/5..3.5/5..4.5/55/5 Apr 2014 8,499ebay.com
Note: (+ +) highly recommended; (+) recommended; (o) reviewed; (..) not available.
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Care should be taken when interpreting the review scores above, though. The assessments were made in relation to similar cameras of the same technological generation. A score, therefore, has to be seen in close connection to the price and market introduction time of the camera, and comparisons of ratings among very different cameras or across long time periods have little meaning. Also, please note that some of the review sites have changed their methodology and reporting over time.

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Other camera comparisons

Did this review help to inform your camera decision process? In case you are interested in seeing how other cameras pair up, just make a corresponding selection in the search boxes below. Alternatively, you can follow any of the listed hyperlinks for comparisons that others found interesting.

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    Specifications: Nikon D4S vs Pentax 645D

    Below is a side-by-side comparison of the specs of the two cameras to facilitate a quick review of their differences and common features.

    Camera Specifications
    Camera Model Nikon D4S Pentax 645D
    Camera Type Digital single lens reflex Digital single lens reflex
    Camera Lens Nikon F mount lenses Pentax 645 mount lenses
    Launch Date February 2014 March 2010
    Launch Price USD 6,499 USD 9,995
    Sensor Specs Nikon D4S Pentax 645D
    Sensor Technology CMOS CCD
    Sensor Format Full Frame Sensor Medium Format Sensor
    Sensor Size 36.0 x 23.9 mm 44.0 x 33.0 mm
    Sensor Area 860.4 mm2 1452 mm2
    Sensor Diagonal 43.2 mm 55 mm
    Crop Factor 1.0x 0.79x
    Sensor Resolution 16.2 Megapixels 39.5 Megapixels
    Image Resolution 4928 x 3280 pixels 7264 x 5440 pixels
    Pixel Pitch 7.29 μm 6.06 μm
    Pixel Density 1.88 MP/cm2 2.72 MP/cm2
    Moiré control Anti-Alias filter no AA filter
    Movie Capability 1080/60p Video no Video
    ISO Setting 100 - 25,600 ISO 100 - 1,600 ISO
    ISO Boost 50 - 409,600 ISO no Enhancement
    Image Processor EXPEED 4 PRIME II
    DXO Sensor Quality (score) 89 82
    DXO Color Depth (bits) 24.4 24.6
    DXO Dynamic Range (EV) 13.3 12.6
    DXO Low Light (ISO) 3074 1262
    Screen Specs Nikon D4S Pentax 645D
    Viewfinder Type Optical viewfinder Optical viewfinder
    Viewfinder Field of View 100% 98%
    Viewfinder Magnification 0.70x 0.78x
    Top-Level Screen Control Panel Control Panel
    LCD Framing Live View
    Rear LCD Size 3.2inch 3.0inch
    LCD Resolution 921k dots 921k dots
    LCD Attachment Fixed screen Fixed screen
    Shooting Specs Nikon D4S Pentax 645D
    Focus System Phase-detect AF Phase-detect AF
    Continuous Shooting 11 shutter flaps/s 1.1 shutter flaps/s
    Shutter Life Expectancy400 000 actuations50 000 actuations
    Time-Lapse PhotographyIntervalometer built-inIntervalometer built-in
    Fill Flash no On-Board Flash no On-Board Flash
    Storage Medium CF or XQD cards SDXC cards
    Single or Dual Card Slots Dual card slots Dual card slots
    Connectivity Specs Nikon D4S Pentax 645D
    External Flash Hotshoe Hotshoe
    Studio Flash PC Sync socket PC Sync socket
    USB Connector USB 2.0 USB 2.0
    HDMI Port mini HDMI no HDMI
    Microphone Port External MIC port no MIC socket
    Headphone Socket Headphone port no Headphone port
    Wifi Support no Wifi no Wifi
    Body Specs Nikon D4S Pentax 645D
    Environmental SealingWeathersealed bodyWeathersealed body
    Battery Type Nikon EN-EL18a Pentax D-LI90
    Battery Life (CIPA)3020 shots per charge800 shots per charge
    Body Dimensions 160 x 157 x 91 mm
    (6.3 x 6.2 x 3.6 in)
    156 x 117 x 119 mm
    (6.1 x 4.6 x 4.7 in)
    Camera Weight 1350 g (47.6 oz) 1480 g (52.2 oz)
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